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Genovations™ testing

Genovations testing evaluates specific portions of the genetic code that vary from person to person.

These variations are called single nucleotide polymorphisms, or SNPs (pronounced “snips”) for short. Everyone has SNPs – they’re what make people different from one another – our hair color, our height, our voice, even key aspects of our personality. SNPs are the very seat of our individuality.

SNPs also affect our health. Some SNPs can make people more susceptible or more resistant to common diseases. Others may make the body respond differently to certain diets or lifestyle habits. SNPs can even affect whether certain drugs are likely to have severe side effects or not.By evaluating these health-related SNPs, Genovations testing allows physicians to develop preventivestrategies that are tailored to each patient’s unique genetic makeup and health risks. This helps to reducethe guesswork that results from using “one-size-fits-all” approach to preventive medicine.

What conditions does Genovations test for?

Genovations testing focuses only on SNPs in the genetic code that are associated with common healthconditions, such as heart disease, osteoporosis, allergies and asthma, for which simple treatmentstrategies are known to reduce risk. Genovations testing also evaluates SNPs that can affect how aperson’s body is likely to respond to certain medications, nutrients, diets, and lifestyle factors.Genovations testing does not evaluate SNPs for conditions or diseases whose risk cannot be modified.

By evaluating a carefully selected group of genetic variants in a patient, each Genovations™ profile provides a previously unseen "glimpse" into that person’s potential health future, empowering the physician to modify the expression of disease years before a condition begins to develop. This allows the physician to:

  • Identify "hidden" gene mutations that may promote chronic disease
  • Gain earlier advanced warning of disease susceptibility in each patient
  • Determine cumulative risk associated with specific, easily identified mutations
  • Intervene much earlier in the pre-disease state
  • Modify gene expression through more precise, targeted, individualized interventions
  • Identify key target areas on which to focus follow-up
  • Monitor therapeutic effectiveness of intervention strategies with laboratory testing

Gastrointestinal disorders have a major impact on health. One recent study found that during a three-month period nearly 70% of American households experienced one or more gastrointestinal symptom.1

Maldigestion, malabsorption and abnormal gut flora and ecology, as well as many complex chronic illnesses and symptoms, lie at the root of most common GI complaints. Thus, nutrition and digestive processes are central to long-term health. Great Smokies’ Comprehensive Digestive Stool Analysis (CDSA) provides clinicians with a critical tool for evaluating the status of the GI tract. This one test can tell you why so many of your symptoms never go away, even if they are not digestion related! The good news is that many insurance companies do cover this test.

Ever wonder what you hormones really are doing? Depending on the test ordered a serum or salivary sample will provide lots of information on your true hormonal status. Specific tests are available for HRT replacement, menopause or perimenopausal women.

Toxic Waste in Your Body?

Chronic health problems can develop from your body's impaired detoxification ability. Uncover the link between your symptoms and your liver function.

In today's world of processed foods and pollution, toxic substances exist almost everywhere. They are in the food you eat, the water you drink (from fertilizers, chemicals and other additives such as colorings and preservatives), and the air you breathe (from automobile emissions, pesticides and industrial pollutants). Some of the body's own compounds must be detoxified as well. Many people talk about toxins and try all types of detoxification procedures too. With this test we can pin point aspects of liver detoxification pathways and with knowledge correct the pathway. In my opinion this needs to be done before many other procedures are considered.

This test reveals important clinical information about:

- Thirteen organic acids that specifically reflect carbohydrate metabolism, mitochondrial function, and beta-oxidation of fatty acids

- Mitochondrial dysfunction which may be underlying chronic symptoms of fibromyalgia, fatigue, malaise, hypotonia (loss of muscle tone), acid-base imbalance, low exercise tolerance, muscle/joint pain, or headache

- Acquired errors of organic acid metabolism that can arise from toxic exposure, nutrient deficiency, intestinal dysbiosis, dysglycemia, oxidative stress, poor diet, and other causes

Over a lifetime, these toxic elements may accumulate inside the human body in tissue such as fat and bone, being broken down and eliminated very slowly. Eventually, this increasing toxic burden can trigger a variety of physical and cognitive disorders, including depression, anxiety, memory loss, and fatigue. Even at relatively low levels, toxic elements have the destructive capability to damage nerves and tissue; strong clinical evidence points to their potential role in early neurodevelopment disorders, such as Attention-Deficit Hyperactivity Disorder, as well as in neurodegenerative conditions of aging such as Parkinson's and Alzheimer's disease. Heart disease, impaired kidney function, respiratory illness, weakened immune function, gastrointestinal dysfunction, and increased cancer risk have also been linked to chronic toxic element exposure.

Hair analysis or urine test can be ordered for measurements of toxic and vital elements.

Call or ask me if this test would be a good idea for you.


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